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(AP Photo/Courtesy of Michael Jackson)
In this May 6, 2009 image released courtesy of Michael Jackson, pop star Michael Jackson is shown in Los Angeles during rehearsals for his upcoming concert in London. Jackson, 50, died in Los Angeles on Thursday, June 25, 2009.
"He wasn't looking to get high or feel good and sedated from drugs," she said. "This was a person who was not on drugs. This was a person who was seeking help, desperately, to get some sleep, to get some rest."
Jackson was rehearsing hard for what would have been his big comeback _ his "This Is It" tour, a series of performances that would have strained his aging dancer's body. Also, pain had been a part of his life since 1984, when his scalp was severely burned during a Pepsi commercial shoot.
"The Incredible Hulk" star Lou Ferrigno, who's been working out with Jackson for the past several months, said Jackson was focused on health.
"When he was with me, he wasn't different. He wasn't stoned. He wasn't high. He wasn't being aloof or speedy. Never talked about drugs," Ferrigno said. "I've never seen him take drugs. He was always talking about nutrition."
Several months ago, Jackson had begun badgering Lee about Diprivan, also known as Propofol, Lee said. It is an intravenous anesthetic drug widely used in operating rooms to induce unconsciousness. It is generally given through an IV needle in the hand.
Patients given Propofol take less time to regain consciousness than those administered certain other drugs, and they report waking up more clear-headed and refreshed, said University of Chicago psychopharmacologist James Zacny.
It has also been implicated in drug abuse, with people using it to "chill out" or to commit suicide, Zacny said. Accidental deaths linked to abuse have been reported. The powerful drug has a very narrow therapeutic window, meaning it doesn't take doses much larger than the medically recommended amount to stop a person's breathing.
An overdose that stops breathing can result in a buildup of carbon dioxide, causing the heart to beat erratically and leading to cardiac arrest, said Dr. John Dombrowski, a member of the board of directors of the American Society of Anesthesiologists.
Because it is given intravenously and is not the kind of prescription drug typically available from pharmacists, abuse cases have involved anesthesiologists, nurses and other hospital staffers with easy access to the drug, Zacny said.
In recent months, Lee said, Jackson waved away her warnings about it.
